Abstract Background Drawing genotype-to-phenotype maps in tumors is of paramount importance for understanding tumor heterogeneity.Assignment of single cells to their tumor clones of origin can be approached by matching the genotypes of the clones to the mutations found in RNA sequencing of the cells.The confidence of the cell-to-clone mapping can b
Structural control and (re)mobilization of the extinct Haveri Au-Cu deposit, southern Finland
The extinct Haveri Au-Cu deposit is located within mafic metalavas and mafic/ intermediate banded biomat for sale rocks of the Haveri Formation, in the western part of the Paleoproterozoic Tampere Schist Belt.The sulfide-bearing banded rocks display a large E-W trending fold structure in magnetic and electromagnetic maps.Field evidence suggest that
Solving real-world optimization tasks using physics-informed neural computing
Abstract Optimization tasks are essential in modern engineering fields such as chip design, spacecraft trajectory determination, and reactor scenario development.Recently, machine learning applications, including deep reinforcement learning (RL) and genetic algorithms (GA), have emerged product in these real-world optimization tasks.We introduce a
Imaging features in calcinosis circumscripta, a rare type of subcutaneous calcification in localized scleroderma
Calcinosis cutis circumscripta is a rare condition in which abnormal deposition of calcium seen in the dermis and subcutaneous tissue, it is associated with localized scleroderma.A 30-year-old female presented with an area of extensive calcification biomat for sale involving the right gluteal region, lateral aspect of right thigh and a small area o
Proposal of a new surgical technique to repair gauge earlobe defect
Earlobes deformities caused by adornments and ornaments are prevalent.The use of plugs and piercings in this topography generates a large partial cleft in the depileve easy clean earlobes, which causes aesthetic and social damage when abandoning its use.The literature has already proposed several surgical techniques to correct defects in the earlob